Asian Journal of Dental Sciences

A Review on Pemphigus

U. Prathusha *

Department of Oral Pathology, Chettinad Dental College and Research Institute, Kelambakkam, India.

A. H. Harini Priya

Department of Oral Pathology, Chettinad Dental College and Research Institute, Kelambakkam, India.

R. Sathishmuthukumar

Department of Oral Pathology, Chettinad Dental College and Research Institute, Kelambakkam, India.

. Nachiammai

Department of Oral Pathology, Chettinad Dental College and Research Institute, Kelambakkam, India.

Serena Florence

Department of Oral Pathology, Chettinad Dental College and Research Institute, Kelambakkam, India.

J. Rebecca Elizabeth Susanna

Department of Oral Pathology, Chettinad Dental College and Research Institute, Kelambakkam, India.

*Author to whom correspondence should be addressed.

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Abstract

Autoimmune bullous diseases is a heterogeneous group of disorders that is characterized by intraepithelial or sub epithelial blistering caused by formation of autoantibodies targeted against structures essential for integrity of skin and mucous membrane. One such type of autoimmune vesiculobullous disease is Pemphigus, which affects the skin and the mucous membrane. There are different types of pemphigus based on the clinical features, histopathological features and the specific antigens against which autoantibodies have been produced. This review gives an overview on thedifferent types of Pemphigus with its clinical, histopathological and immunopathological characteristics and its treatment.

Keywords: Vesiculobullous lesions, pemphigus, pemphigus variants, histopathology, immunopatho-logy; treatment.

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